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KMID : 0358419710140060021
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Korean Journal of Obstetrics and Gynecology
1971 Volume.14 No. 6 p.21 ~ p.29
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Immunologic and Biologic Titers of Human Chorionic Gonadotropin in Urine Throughout Normal and Abnormal Pregnancies
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宋龍德/Song, Yong Duck
張潤錫/羅建榮/Chang, Yoon Souk/Rha, Keun Yung
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Abstract
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The usefulness of guantitative immunologic test for human chorionic gonadotropin in the urine was. studied. .A compartaive study of titration between the slide immunologic and biologic test was. given and the results were as follows;
1. 127 cases of normal pregnancy, 10 cases of non-pregnancy, 1 ´case of destru ctive mole, 4 cases of hydatidiform Mole, 8 cases of chorio-carcinoma, totaling: 145 cases were studied.
2. Both tests were negative in non-preg, women.
3. The peak level of H.C.G.excretion in urine in normal pregnancy takes place´ between 6 and 14 weeks (esp. 8-l0wks) following the last menstrual period. There is then a gradual decrease during the second trimester, and slight increase during the third trimester.
4. The H.C.G. titers of immunologic preg test in urine is higher than of´ biologic test, but the patterns of both curves are not different.
5. Diagnostic accuracy was found to be 98.0% with slide test, and 77.0% with: frog test, during 6-14 wks of gestation period, and the general diagnostic accuracy was 92.8% with slide test, 48.4% with frog test.
6. The H.C.G. titers were higher in the 4 cases of hydatidiform mole than theupper limit in the normal pregnancy.
7. The slide immunologic pregnancy test was found to be a rapid, accurate,. but still expensive, and be able to. evaluate the H.C.G. titers with this method.
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